Table of Contents
Patients, Families and Friends
Health Care Providers
|Web Update - 2010-12 - December|
|News - Web Update - 2010-12 - December|
|Tuesday, 21 December 2010 15:56|
Fatal 1918 Pneumonia Case Complicated by Erythrocyte Sickling http://www.cdc.gov/eid/content/16/12/pdfs/10-1376.pdf
The year 2010 marks the 100th anniversary of Herrick’s original case description of what is now known as sickle cell anemia Additional case reports followed in 1911 and 1915; in 1922, Mason described a fourth case and coined the term sickle cell anemia (In 1949, Pauling et al. published an important study that identified differences in the electrophoretic mobilities of normal and sickled erythrocytes The inheritance pattern of sickle cell anemia was determined in 1949; in 1957, Ingram identified the single amino acid change in hemoglobin S . Patients with sickle cell anemia are at markedly increased risk for infections with several bacteria, including Streptococcus pneumoniae, and emerging viral infections such as pandemic influenza. We report a retrospectively identified case of fatal bacterial pneumonia complicated by abundant erythrocyte sickling in a patient bearing the sickle cell trait. The patient’s illness occurred in July 1918, representing one of the first identified symptomatic cases of sickle cell trait.
A SOD-cutting ceremony has been performed for work to begin on the construction of an ultra-modern Blood and Sickle Cell centre at the Komfo Anokye Teaching Hospital (KATH) in Kumasi, Ghana. http://www.modernghana.com/news/306308/1/1366m-blood-amp-sickle-cell-centre-for-kath.html
A Vanderbilt-Meharry Center for Excellence in Sickle Cell Disease has been established by Vanderbilt University Medical Center and Meharry Medical College. http://www.mc.vanderbilt.edu/reporter/index.html?ID=9510
The Center will seek to bring high quality care to people with sickle cell disease (SCD) that is seamless and lifelong. Michael DeBaun, M.D., MPH, an internationally renowned researcher in the area of SCD, has been named director of the new Center for Excellence. DeBaun, recently named vice chair for Clinical Affairs for the Vanderbilt Department of Pediatrics, arrives at Vanderbilt in November from Washington University in St. Louis.
DeBaun says he envisions teams of specialists from Vanderbilt and Meharry working shoulder to shoulder with community physicians to care for those with sickle cell disease. He also envisions family-centered care, and active involvement of the community within the Center.
226 Abstracts published about Sickle Cell disease in the December ASH meeting http://ash.confex.com/ash/2010/webprogram/start.html#srch=words%7Csickle%20cell%7Cmethod%7Cand%7Cpge%7C1
Some of the titles are:
Hydroxyurea Therapy Reduces Mortality Among Children with Sickle Cell Disease http://ash.confex.com/ash/2010/webprogram/Paper30782.html
A Randomized Trial of the Safety and Benefit of Transfusion Vs. Standard Care In the Prevention of Sickle Cell-Related Complications In Adults: a Preliminary Report From the Phase II NHLBI Comprehensive Sickle Cell Centers (CSCC) Study of Neuropsychological Dysfunction and Neuroimaging Abnormalities In Neurologically Intact Adult Patients with Sickle Cell Disease http://ash.confex.com/ash/2010/webprogram/Paper33488.html
Stroke with Transfusions Changing to Hydroxyurea (SWiTCH): A Phase 3 Randomized Clinical Trial for Treatment of Children with Sickle Cell Anemia, Previous Stroke, and Iron Overload http://ash.confex.com/ash/2010/webprogram/Paper31105.html
High Mortality Among Children with Sickle Cell Anemia and Stroke Who Discontinue Chronic Blood Transfusion After Transition to An Adult Program http://ash.confex.com/ash/2010/webprogram/Paper29089.html
Articles in the Medical Literature
http://nmanet.org/index.php/pub_past_issues/november_2010 for the full text
JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION VOL. 102, NO. 11, NOVEMBER 20
Maryland Genetics Sickle Cell Information http://fha.maryland.gov/genetics/sickle_pro.cfm
The Collegiate Sports Medicine Foundation – Center for College and University Sports Medicine http://www.csmfoundation.org/Sickle_Cell_Athlete.html
5th Annual Sickle Cell Disease Research and Educational Symposium & Annual National Sickle Cell Disease Scientific Meeting Grant Writing Institute (GWI), February 21-22, 2011
Sickle Cell in Focus 2011 16-17 June, London Hosted by Swee Lay Thein, Professor of Molecular Haematology King’s College London and Consultant Haematologist King’s College Hospital
ENERCA Educational Day on Sickle Cell Disease and Thalassaemias 4 March 201, London
Hosted by Swee Lay Thein, Professor of Molecular Haematology King’s College London and Consultant Haematologist King’s College Hospital
8th annual California statewide sickle cell symposium will April 1st and 2nd, 2011 in Buena Park, CA. More information to come.